A Woman Became Obese After a Poop Transplant

Scientists have eff for a while that gut bacteria can toy a profound part in the weighting of computer mouse . Now we have a case account in humans that is not entirely surprising : A adult female gained 36 pounds and became corpulent in the 16 month after a fecal graft .

The 32 - year - old woman had maintained an average weight her entire life , fit in to acase report inOpen Forum Infection Disease . Then she fell tired of with Clostridium difficile , a bowel infection that is difficult to bring around with antibiotics but very leisurely to treat with a fecal transplant , which supervene upon the intact gut microbiota with one from someone healthy . The adult female ’s donor was her 16 - year - erstwhile girl , who weighed 140 pounds at the time but afterward give-up the ghost up to 170 punt .

After her fecal transplant , the woman set forth pack on pound and could n’t lose it , despite “ medically monitor liquid protein dieting and exercise programme . ” She ended up at 177 pounds and suffered from constipation and bad digestion .

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It ’s impossible to draw conclusions from any single patient , of course , but this casing is interesting against the broader context of what we sleep together about the gut microbiota and weight . A decade of studies in micehave found that those implanted with the gut microbiota of corpulent human being will become obese , too , despite eating the same diet as those give the microbiota of non - obese human being . Gastric ringway surgery in mice alsodrastically shifts the gut microbiota , and it could be one reason for why the operating theater is so effective for turn a loss exercising weight .

And then there are prophylactic questions . The FDA backed off from closely regulating fecal transplant in 2013 — which manysaw as the right decision — but the appendage of screening giver is not standardized . There are millions of bacterium involved in a fecal transplant , and we do n’t really know what each one does .

The authors of the case report , which includeColleen Kelly at Brown University , one of the pioneering physician to study using faecal graft to treat C. difficile , compose they now no longer use obese donors . Poop is serious medical commercial enterprise , and sometimes it can go wrong . [ Open Forum Infectious DiseasesviaBBC ]

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