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When it hail to learning from fault , human and rat think alike , research suggests .
In a written report that go after how humans and their rodent cousin adapted to errors during a fourth dimension appraisal task , the two metal money showed similar brain activity in the median head-on cortex ( MFC ) , which sends signals that synchronize neurons in the part of the brain that keep in line movement .
As in rats, low-frequency brainwaves in the human medial frontal cortex change from low-power (blue) to high-power (red-orange) after the recognition of a mistake.
The finding suggest rats could answer as models for study human adaptative control , the unconscious process of modifying choices based on experience . This cognition could be useful in treating psychiatric disease , such as obsessional driven disorderliness , depression and schizophrenic disorder , the researchers say . [ Top 10 Controversial Psychiatric Disorders ]
" With this scab model of adaptative control , we are now able to try if new drug or other discourse procedures hike up the integrity of this system , " written report researcher James Cavanagh , now a psychology prof at the University of New Mexico , in Albuquerque , said in a statement .
lesion to the MFC in homo and other creature are have intercourse to make impaired performance in tasks that requirelearning from misapprehension , such as a false start in a raceway . But the chemical mechanism for how MFC achieved this command was n’t known .
Cavanagh and his workfellow at Brown and Yale Universities measured the brainwaves of informer and humans as both perform a task that necessitate estimating time in response to a clew .
The researcher attend an increase in low - frequency brainwaves in the MFC of rats and humans after they made errors during the task . The brain activity in this area was synchronized with activeness in the motor cortex , the part of the brain thatcontrols brawn move .
When the scientist used drugs to demobilise the MFC in the rats , the animals were worse at see from their mistakes on the task , and their MFC brainwaves were less in sync with the motor cortex .
The results , detail today ( Oct. 20 ) in the diary Nature Neuroscience , " describe a new mechanism for behavioral adaption through low - frequence oscillations , " the authors write . The findings paint a picture gnawer could be a good fashion model for testing novel drug or mastermind stimulation discussion for diseases postulate problems with adaptative control , they add .
