01of 05Mayim BialikAlice S. Hall/NBC/NBCU Photo Bank via Getty Images; Kevin Mazur/Getty Images for TNTThen:Serving as the show’s eponymous protagonist, Bialik played Blossom Russo — the sole female who navigated life as a teen,andwas responsible for making the floppy hat popular among viewers.Now:WhileBlossomgave Bialik her big acting break, theGirling Upauthor and mom of two scored accolades for her role in the ultra-successfulThe Big Bang Theory —alongside co-star Johnny Galecki, whomshe had her first kisswith onBlossom. The comedic turn became an easy transition for Bialik, who is also a neuroscientist (like her character) in real life. Now she’s one of the two new hosts ofJeopardy!following Alex Trebek’s passing.She also stars onCall Me Kat —and recently reunited with herBlossomcostars for an episode.

01of 05

Mayim Bialik

Alice S. Hall/NBC/NBCU Photo Bank via Getty Images; Kevin Mazur/Getty Images for TNT

mayim-bialik-2000

Then:Serving as the show’s eponymous protagonist, Bialik played Blossom Russo — the sole female who navigated life as a teen,andwas responsible for making the floppy hat popular among viewers.

Now:WhileBlossomgave Bialik her big acting break, theGirling Upauthor and mom of two scored accolades for her role in the ultra-successfulThe Big Bang Theory —alongside co-star Johnny Galecki, whomshe had her first kisswith onBlossom. The comedic turn became an easy transition for Bialik, who is also a neuroscientist (like her character) in real life. Now she’s one of the two new hosts ofJeopardy!following Alex Trebek’s passing.She also stars onCall Me Kat —and recently reunited with herBlossomcostars for an episode.

02of 05Jenna von OÿTouchstone Pictures/ABC via Getty Images; Charles Sykes/Bravo/NBCU Photo Bank via Getty ImagesThen:Every girl needs a best friend — and for Blossom Russo, no one was a better partner than von Oÿ’s quirky Six Dorothy Lemeure. Despite serving as Blossom’s sidekick, Six faced a handful of life-altering events, which included alcoholism and a pregnancy scare.Now:AfterBlossom, von Oÿ starred inThe Parkersfrom 1999 to 2004. The actress has also made guest appearances on7th HeavenandCold Case, as well as voiceover work, and released her second book,Situation Momedy: A Very Special Episode in Toddlerdom. She shares two daughters with ex Brad Bratcher.

02of 05

Jenna von Oÿ

Touchstone Pictures/ABC via Getty Images; Charles Sykes/Bravo/NBCU Photo Bank via Getty Images

jenna-von-oy-2000

Then:Every girl needs a best friend — and for Blossom Russo, no one was a better partner than von Oÿ’s quirky Six Dorothy Lemeure. Despite serving as Blossom’s sidekick, Six faced a handful of life-altering events, which included alcoholism and a pregnancy scare.

Now:AfterBlossom, von Oÿ starred inThe Parkersfrom 1999 to 2004. The actress has also made guest appearances on7th HeavenandCold Case, as well as voiceover work, and released her second book,Situation Momedy: A Very Special Episode in Toddlerdom. She shares two daughters with ex Brad Bratcher.

03of 05

Joey Lawrence

Touchstone Pictures/ABC via Getty Images;

joey-lawrence-2000

Then:Blossom’s older brother, Joey, wasn’t just the object of Six’s affection, but he also served as the show’s comedic relief with his now-iconic “Whoa!” catchphrase.

04of 05

Michael Stoyanov

Alice S. Hall/NBC/NBCU Photo Bank via Getty Images; Al Pereira/Getty Images

michael-stoyanov-1-2000

Then:Stoyanov played Tony, a recovering drug and alcohol addict, and older brother to Blossom and Joey, who eventually became a paramedic.

05of 05

Ted Wass

Touchstone Pictures/ABC via Getty Images; Michael Ansell/ABC via Getty Images

ted-wass-2000

Then:As Blossom, Joey and Tony’s father Nick, Wass’s character took on the role of a single parent after his wife — and the kids' mom — left the family to pursue her career.

source: people.com